PHARMACOMICROBIOMICS AND PERSONALIZED MEDICINE IN COLORECTAL CANCER THERAPHIES
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Margarita Poza Domínguez |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2021 to 31/12/2023 |
| Address | 1ºFacultade de Ciencias-Laboratorio de Microbiología -CAmpus Zapateira 15008 A Coruña 2ºServizo de Microbioloxía, 3ªplanta, edificio sur, Hospital Universitario, As Xubias 15006 A Coruña |
| Phone | 981176552 |
| Website | http://www.inibic.es/grupos/microbiologia/lineas.html |
| UNESCO codes |
MICROBIOLOGIA (241400) MICROBIOLOGIA CLINICA (ver 2414)1 (320103) |
| Socioeconomic codes |
R&D related to Medical Sciences - financed from other sources than GUF (13.3) R&D related to Medical Sciences - financed from GUF (12.3) R&D related to Natural Sciences - financed from GUF (12.1) Health (07) |
| Research lines |
Microbiome and Health pharmacomicrobiomics Microbial genomics Microbial pathogenesis Microbial Virulence Factors Microbiome and cancer COVID-19 AND WASTEWATER SARS-COV-2 sequencing |
| Keywords | Clinical microbiology, nanotechnology, microbiome, pharmacomicrobiomics, microbiome and cancer, molecular microbiology, microbial virulence, genomics, transcriptomics |
| Services offered |
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PHARMACOMICROBIOMICS AND PERSONALIZED MEDICINE IN COLORECTAL CANCER THERAPHIES
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Margarita Poza Domínguez |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2021 to 31/12/2023 |
Epidemiología genómica y monitorización en tiempo real del SARS-CoV-2 en Galicia
| Funding entity | Xunta de Galicia |
| Main researches | David Posada |
| Type | Proyecto Programas Autonomicos |
| Dates | From 04/11/2020 to 30/12/2021 |
EPICOVIGAL; Epidemiología genómica y monitorización en tiempo real del SARS-CoV-2 en Galicia
| Funding entity | BANCO SANTANDER CENTRAL HISPANO |
| Main researches | David Posada |
| Type | Proyecto Programas Nacionales |
| Dates | From 15/10/2020 to 14/10/2021 |
COVID-RES_ VIGILANCIA EPIDEMIOLÓGICA EN AGUAS RESIDUALES EN RESIDENCIAS DE MAYORES Y CENTROS DE DISCAPACIDAD
| Funding entity | Consellería de Política Social de la Xunta de Galicia |
| Type | Contrato |
| Dates | From 17/12/2020 to 17/04/2021 |
COVIDBENS II/SEQCOVIDBENS; MONITORIZACIÓN Y SECUENCIACÓN DE LAS VARIANTES DEL VIRUS SARS-CoV-2 EN AGUAS RESIDUALES
| Funding entity | EDAR BENS SA Y AUGAS DE GALICIA |
| Main researches | Margarita Poza Domínguez |
| Type | Contrato |
| Dates | From 18/11/2020 to 17/05/2021 |
COVIDBENS I; MONITORIZACIÓN DEL VIRUS SARS-CoV-2 EN LAS INSTALACIONES GESTIONADAS POR EDAR BENS S.A
| Funding entity | EDAR BENS SA |
| Main researches | Margarita Poza Domínguez |
| Type | Contrato |
| Dates | From 11/05/2020 to 10/10/2020 |
COVIDBENS: MONITORIZACIÓN DEL VIRUS SARS-CoV-2 EN LAS INSTALACIONES GESTIONADAS POR EDAR BENS S.A
| Funding entity | EDAR Bens S.A. y AGUAS DE GALICIA |
| Main researches | Margarita Poza Domínguez |
| Type | Contrato |
| Dates | From 11/04/2020 to 10/10/2020 |
CARBAPENEMASES RESISTANCE DATABASE
| Funding entity | Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica-SEIMC |
| Type | Contrato |
| Dates | From 01/01/2019 to 31/12/2020 |
Evaluación de nuevas estrategias antimicrobianas mediante silenciamiento de ARN vehiculizado en nanocápsulas e inhibidores enzimáticos
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Margarita Poza Domínguez y Alejandro Beceiro Casas |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2018 to 31/12/2020 |
Ayudas para la consolidación y estructuración de unidades de investigación competitivas de organismos públicos de investigación.
| Funding entity | Xunta de Galicia |
| Main researches | Germán Bou Arévalo |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/10/2016 to 30/09/2019 |
Estudio de los mecanismos implicados en la colonización y epidemicidad del patógeno nosocomial K. pneumoniae : búsqueda de nuevas estrategias para erradicar una infección
| Funding entity | Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica-SEIMC |
| Main researches | Astrid Pérez Gómez |
| Type | Proyecto Otros Programas |
| Dates | From 01/06/2016 to 31/05/2017 |
Identification of the mechanism of action of a novel series of compounds active against Acinetobacter baumannii
| Funding entity | ABAC Therapeutics |
| Main researches | Germán Bou Arévalo |
| Type | Contrato |
| Dates | From 01/06/2016 to 31/05/2020 |
Nuevas estrategias frente al patógeno multirresistente Acinetobacter baumannii: silenciamiento (siRNA) bacteriano y desarrollo de nuevos inhibidores. Estudios preclínicos.
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Margarita Poza Domínguez y Alejandro Beceiro Casas |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2015 to 31/12/2017 |
Genómica y Transcriptómica del Biofilm de Acinetobacter baumannii
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Margarita Poza Domínguez |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2012 to 31/12/2015 |
Mecanismos de Regulación de Resistencia Antibiótica y Virulencia en el Microorganismo Patógeno Nosocomial Acinetobacter baumannii
| Funding entity | Instituto de Salud Carlos III (ISCIII) |
| Main researches | Germán Bou Arévalo |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2009 to 31/12/2011 |
Estudio de las Diferencias de Expresión Génica Asociadas con Resistencia a Antibióticos en Acinetobacter baumannii.
| Funding entity | Consellería de Sanidade, Xunta de Galicia |
| Main researches | Margarita Poza Domínguez |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2008 to 31/12/2011 |
Axudas para a consolidación das unidades de investigación do sistema galego de investigación e innovación
| Funding entity | Xunta de Galicia |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/10/2007 to 31/12/2008 |
Estudio de Resistencia Antibiótica, Virulencia, y Epidemicidad en el Microorganismo Patógeno Nosocomial Acinetobacter baumannii mediante Análisis Proteómico
| Funding entity | Consellería de Sanidade. Xunta de Galicia. |
| Main researches | Germán Bou Arévalo |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2007 to 31/12/2010 |
Clonación y expresión industrial del gen de la quimosina de Bubalus arnee bubalis
| Funding entity | Consellería de Innovación e Industria de la Xunta de Galicia. |
| Main researches | Tomás González Villa. |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2006 to 31/12/2008 |
Eliminación de Naftaleno en Aguas Marinas Contaminadas por Vertidos de Petróleo Mediante Inmovilización de Bacterias Degradadoras
| Funding entity | FUNDACIÓN ARAO |
| Main researches | Tomás González Villa |
| Type | Proyecto Otros Programas |
| Dates | From 01/01/2005 to 31/12/2007 |
Obtención de microorganismos productores de quimosina de búfalo para la elaboración de nuevas masas queseras
| Funding entity | Xunta de Galicia |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2005 to 31/12/2008 |
Clonación y expresión del gen de la quimosina de Bubalus arnee bubalis en E. coli y levaduras
| Funding entity | Ministerio de Educación y Ciencia y empresa BioGes-Starters (León). CICYT-PETRI. Plan Nacional (PETRI/TRACE) |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2005 to 31/12/2007 |
Formulación galénica de enzimas líticos de origen microbiano para el tratamiento de la candidiasis vaginal
| Funding entity | Xunta de Galicia |
| Main researches | Juan José Torres Labandeira |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2004 to 31/12/2007 |
Clonación del gen de la proteasa aspártica de Bacillus licheniformis en E. coli y Pichia pastoris.
| Funding entity | Xunta de Galicia |
| Main researches | Tomás G. Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2002 to 31/12/2005 |
Aprovechamiento de una nueva bacteria Gordonia jacobaea MV-1- para la producción industrial de cetocarotenos (cantaxantina): mejora de la producción mediante mutagénesis
| Funding entity | Ministerio de Ciencia y Tecnología y empresa Antaspharma S.L. CICYT-PETRI. Plan Nacional (PETRI/TRACE). |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2002 to 31/12/2005 |
Enzimas hidrolíticos extracelulares de Saccharomyces cerevisiae como marcadores de crianza y envejecimiento de los vinos
| Funding entity | Xunta de Galicia |
| Main researches | Tomás G. Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2002 to 31/12/2005 |
Mejora y explotación en alimentación animal de una nueva bacteria, Gordonia jacobaea, superproductora de cantaxantina
| Funding entity | Xunta de Galicia |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2001 to 31/12/2004 |
Clonación del gen de la proteasa aspártica de Bacillus licheniformis subsp. caseinocoagulans en E. coli y Pichia pastoris. Uso para la elaboración de masas queseras
| Funding entity | Ministerio de Economía |
| Main researches | Tomás González Villa |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/2001 to 31/12/2004 |
Estudio y caracterización dos enzimas pépticos producidos por especies dos xéneros Kluyveromyces y Cryptococcus.
| Funding entity | Xunta de Galicia |
| Main researches | Tomás G. Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/07/2000 to 31/12/2000 |
Desenvolvemento dun biorreactor de alto rendemento para a producción intensiva de microalgas mariñas
| Funding entity | Xunta de Galicia |
| Main researches | Tomás G. Villa |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/2000 to 31/12/2001 |
Producción de Natamicina y quimosina por microorganismos
| Funding entity | Secretaría de Estado de Universidades, Investigación y Desarrollo. Dirección General de Enseñanza Superior (DGESIC) |
| Main researches | Tomás G. Villa |
| Type | Proyecto Programas Nacionales |
| Dates | From 01/01/1998 to 31/12/2001 |
Floculación en Saccharomyces cerevisiae: regulación diferencial y dispersión de los genes FLO
| Funding entity | Xunta de Galicia |
| Main researches | Carmen Sieiro Vázquez |
| Type | Proyecto Programas Autonomicos |
| Dates | From 01/01/1997 to 31/12/1998 |
Clonación del gen de la quimosina de la bacteria Myxococcus xanthus en la levadura S. cerevisaie.
| Funding entity | Fundación Empresa-Universidad Gallega (FEUGA) |
| Main researches | Tomás G Villa |
| Type | Proyecto Otros Programas |
| Dates | From 01/01/1996 to 31/12/1998 |
The multispecies microbial cluster ofFusobacterium,Parvimonas,BacteroidesandFaecalibacteriumas aprecision biomarker for colorectal cancer diagnosis
| Authors | Kelly Conde-Pérez, Pablo Aja-Macaya, Elena Buetas, Noelia Trigo-Tasende, Mohammed Nasser-Ali, Soraya Rumbo-Feal, Paula Nión, Elsa Martin-De Arribas, Lara S. Estevez, Begoña Otero-Alén, F.J. Noguera, Ángel Concha, Simón Pardiñas-López, Miguel Carda-Diéguez, Igor Gómez-Randulfe, Nieves Martínez-Lago, Susana Ladra, Luis M. A. Aparicio, Germán Bou, Alex Mira, Juan A. Vallejo, Margarita Poza |
| Journal | Molecular Oncology |
| DOI | https://doi.org/10.1002/1878-0261.13604 |
Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, Spain
| Authors | Noelia Trigo-Tasende, Juan A. Vallejo, Soraya Rumbo-Feal, Kelly Conde-Pérez, Mohammed Nasser-Ali, J. Tarrío-Saavedra, Inés Barbeito, Fernando Lamelo, R. Cao Abad, Susana Ladra, Germán Bou, M Poza |
| Journal | Environments Vol. 10 Num. 11 |
| DOI | https://doi.org/10.3390/environments10110189 |
Modeling the number of people infected with SARS-COV-2 from wastewater viral load in Northwest Spain
| Authors | Juan A. Vallejo, Noelia Trigo-Tasende, Soraya Rumbo-Feal, Kelly Conde-Pérez, Ángel López-Oriona, Inés Barbeito, Manuel Vaamonde, javier Tarrío-Saavedra, Rubén Reif, Susana Ladra, Bruno K. Rodiño Janeiro, Mohammed Nasser-Ali, Ángeles Cid, Maria C. Veiga, Antón Acevedo, Carlos Lamora, Germán Bou, Ricardo Cao, Margarita Poza |
| Journal | SCIENCE OF THE TOTAL ENVIRONMENT Vol. 811 |
| DOI | https://doi.org/10.1016/j.scitotenv.2021.152334 |
Antisense inhibition of lpxB gene expression in Acinetobacter baumannii by peptide-PNA conjugates and synergy with colistin
| Authors | Marta Martinez-Guitián, Juan Carlos Vázquez-Ucha, L Alvarez-Fraga, Kelly Conde-Pérez, Germán Bou, M Poza * corresponding author, Alejandro Beceiro |
| Journal | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY |
Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii.
| Authors | Juan Carlos Vázquez-Ucha, Marta Martinez-Guitián, Maneiro M, Conde-Pérez K, Álvarez-Fraga L, Torrens G, Oliver A, Buynak JD, Bonomo RA, Bou-Arévalo G, González-Bello C, M Poza, Alejandro Beceiro |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 60 Num. 10 |
| DOI | https://doi.org/10.1128/aac.01092-19. |
Involvement of HisF in the Persistence of Acinetobacter baumannii During a Pneumonia Infection
| Authors | Marta Martinez-Guitián, Vazquez-Ucha, Juan C., L Alvarez-Fraga, Kelly Conde-Pérez, Cristina Lasarte-Monterrubio, Andres Vallejo, Juan, Germán Bou, M Poza * corresponding author, Alejandro Beceiro |
| Journal | Frontiers in Cellular and Infection Microbiology Vol. 29 Num. 9 |
Draft Genome Sequences of Two Epidemic OXA-48-Producing Klebsiella pneumoniae Clinical Strains Isolated during a Large Outbreak in Spain
| Authors | Gato, E., Alvarez-Fraga, L., Vallejo, J. A., Rumbo-Feal, S., Martinez-Guitian, M., Alejandro Beceiro, M Poza, Germán Bou, A Pérez |
| Journal | Genome Announcements Vol. 6 Num. 13 |
| DOI | https://doi.org/10.1128/genomea.00026-18 |
Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii
| Authors | Alvarez-Fraga, Laura, Vazquez-Ucha, Juan C., Martinez-Guitian, Marta, Vallejo, Juan A., Bou, German, Beceiro, Alejandro, Margarita Poza |
| Journal | VIRULENCE Vol. 9 Num. 1 (pages 496 to 509) |
| DOI | https://doi.org/10.1080/21505594.2017.1420451 |
Contribution of the A-baumannii A1S_0114 Gene to the Interaction with Eukaryotic Cells and Virulence
| Authors | Rumbo-Feal, Soraya, Perez, Astrid, Ramelot, Theresa A., Alvarez-Fraga, Laura, Vallejo, Juan A., Beceiro, Alejandro, Ohneck, Emily J., Arivett, Brock A., Merino, Maria, Fiester, Steven E., Kennedy, Michael A., Actis, Luis A., Bou, German, Margarita Poza |
| Journal | Frontiers in Cellular and Infection Microbiology Vol. 7 |
| DOI | https://doi.org/10.3389/fcimb.2017.00108 |
Activity of the beta-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D beta-Lactamases from Acinetobacter baumannii
| Authors | Juan Carlos Vázquez-Ucha, Isabel María Maneiro Estraviz, Martinez-Guitian, Marta, Buynak, John, Bethel, Christopher R., Bonomo, Robert A., Bou, German, Margarita Poza, Gonzalez-Bello, Concepcion, Beceiro, Alejandro |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 61 Num. 11 |
| DOI | https://doi.org/10.1128/aac.01172-17 |
The FhaB/FhaC two-partner secretion system is involved in adhesion of Acinetobacter baumannii AbH12O-A2 strain
| Authors | Perez, A., Merino, M., Rumbo-Feal, S., Alvarez-Fraga, L., Vallejo, J. A., A Beceiro, Ohneck, E. J., Mateos, J., Fernandez-Puente, P., Actis, L. A., M Poza * corresponding author, Bou, G. |
| Journal | VIRULENCE Vol. 8 Num. 6 (pages 959 to 974) |
| DOI | https://doi.org/10.1080/21505594.2016.1262313 |
Global assessment of small RNAs reveals a non-coding transcript involved in biofilm formation and attachment in Acinetobacter baumannii ATCC 17978
| Authors | Alvarez-Fraga, Laura, Rumbo-Feal, Soraya, Perez, Astrid, Gomez, Manuel J., Gayoso, Carmen, Vallejo, Juan A., Ohneck, Emily J., Valle, Jaione, Actis, Luis A., Beceiro, Alejandro, Bou, German, Margarita Poza |
| Journal | PLOS ONE Vol. 12 Num. 8 |
| DOI | https://doi.org/10.1371/journal.pone.0182084 |
Synergy between Colistin and the Signal Peptidase Inhibitor MD3 Is Dependent on the Mechanism of Colistin Resistance in Acinetobacter baumannii
| Authors | Martinez-Guitan, Marta, Vazquez-Ucha, Juan C., Odingo, Joshua, Parish, Tanya, Margarita Poza, Waite, Richard D., Bou, German, Wareham, David W., Beceiro, Alejandro |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 60 Num. 7 (pages 4375 to 4379) |
| DOI | https://doi.org/10.1128/aac.00510-16 |
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48
| Authors | Vallejo, Juan A., Martinez-Guitian, Marta, Vazquez-Ucha, Juan C., Gonzalez-Bello, Concepcion, Margarita Poza, Buynak, John D., Bethel, Christopher R., Bonomo, Robert A., Bou, German, Beceiro, Alejandro |
| Journal | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Vol. 71 Num. 8 (pages 2171 to 2180) |
| DOI | https://doi.org/10.1093/jac/dkw105 |
Genome Sequence of a Clinical Strain of Acinetobacter baumannii Belonging to the ST79/PFGE-HUI-1 Clone Lacking the AdeABC ( Resistance-Nodulation-Cell Division-Type) Efflux Pump
| Authors | María López, Alvarez-Fraga, L., Gato, E., Blasco, L., Poza, M., Fernandez-Garcia, L., Bou, G., Tomas, M. |
| Journal | Genome Announcements Vol. 4 Num. 5 |
| DOI | https://doi.org/10.1128/genomea.00962-16 |
Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cells
| Authors | Alvarez-Fraga, Laura, Perez, Astrid, Rumbo-Feal, Soraya, Merino, Maria, Andres Vallejo, Juan, Ohneck, Emily J., Edelmann, Richard E., Beceiro, Alejandro, Vazquez-Ucha, Juan C., Valle, Jaione, Actis, Luis A., Bou, German, Margarita Poza |
| Journal | VIRULENCE Vol. 7 Num. 4 (pages 443 to 455) |
| DOI | https://doi.org/10.1080/21505594.2016.1145335 |
Quantitative proteomic analysis of host-pathogen interactions: a study of Acinetobacter baumannii responses to host airways
| Authors | Antonio Mendez, Jose, Mateos, Jesus, Beceiro, Alejandro, M López, Tomas, Maria, Margarita Poza, Bou, German |
| Journal | BMC GENOMICS Vol. 16 |
| DOI | https://doi.org/10.1186/s12864-015-1608-z |
Draft Genome Sequence of the Biofilm-Hyperproducing Acinetobacter baumannii Clinical Strain MAR002
| Authors | Alvarez-Fraga, Laura, M López, Merino, Maria, Rumbo-Feal, Soraya, Tomas, Maria, Bou, German, Margarita Poza |
| Journal | Genome Announcements Vol. 3 Num. 4 |
| DOI | https://doi.org/10.1128/genomea.00824-15 |
Nosocomial Outbreak of a Multiresistant Acinetobacter baumannii Expressing OXA-23 Carbapenemase in Spain
| Authors | Merino, Maria, Margarita Poza, Roca, Ignasi, Jose Barba, Maria, Dolores Sousa, Maria, Vila, Jordi, Bou, German |
| Journal | MICROBIAL DRUG RESISTANCE-MECHANISMS EPIDEMIOLOGY AND DISEASE Vol. 20 Num. 4 (pages 259 to 263) |
| DOI | https://doi.org/10.1089/mdr.2013.0127 |
Complete Genome Sequence of the Multiresistant Acinetobacter baumannii Strain AbH12O-A2, Isolated during a Large Outbreak in Spain
| Authors | M Merino, L Alvarez-Fraga, MJ Gómez, AM Aransay, JL Lavín, F Chaves, Bou-Arévalo G, M Poza |
| Journal | Genome Announcements Vol. 2 Num. 6 |
| DOI | https://doi.org/10.1128/genomea.01182-14 |
Identification of a DNA-Damage-Inducible Regulon in Acinetobacter baumannii
| Authors | Aranda, Jesus, Margarita Poza, Shingu-Vazquez, Miguel, Cortes, Pilar, Boyce, John D., Adler, Ben, Barbe, Jordi, Bou, German |
| Journal | JOURNAL OF BACTERIOLOGY Vol. 195 Num. 24 (pages 5577 to 5582) |
| DOI | https://doi.org/10.1128/jb.00853-13 |
Whole Transcriptome Analysis of Acinetobacter baumannii Assessed by RNA-Sequencing Reveals Different mRNA Expression Profiles in Biofilm Compared to Planktonic Cells
| Authors | Rumbo-Feal, Soraya, Gomez, Manuel J., Gayoso, Carmen, Alvarez-Fraga, Laura, Cabral, Maria P., Aransay, Ana M., Rodriguez-Ezpeleta, Naiara, Fullaondo, Ane, Valle, Jaione, Tomas, Maria, Bou, German, Margarita Poza |
| Journal | PLOS ONE Vol. 8 Num. 8 |
| DOI | https://doi.org/10.1371/journal.pone.0072968 |
Involvement of the AcrAB-TolC Efflux Pump in the Resistance, Fitness, and Virulence of Enterobacter cloacae
| Authors | Perez, Astrid, Margarita Poza, Fernandez, Ana, M Fernández, Susana Mallo, Fernandez, Merino, Maria, Rumbo-Feal, Soraya, Cabral, Maria P., Bou, German |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 56 Num. 4 (pages 2084 to 2090) |
| DOI | https://doi.org/10.1128/aac.05509-11 |
Exploring Bacterial Diversity in Hospital Environments by GS-FLX Titanium Pyrosequencing
| Authors | Margarita Poza, Gayoso, Carmen, Gomez, Manuel J., Rumbo-Feal, Soraya, Tomas, Maria, Aranda, Jesus, Ana Fernández, Bou, German |
| Journal | PLOS ONE Vol. 7 Num. 8 |
| DOI | https://doi.org/10.1371/journal.pone.0044105 |
Effect of Transcriptional Activators SoxS, RobA, and RamA on Expression of Multidrug Efflux Pump AcrAB-TolC in Enterobacter cloacae
| Authors | Perez, Astrid, Margarita Poza, Aranda, Jesus, Latasa, Cristina, Javier Medrano, Francisco, Tomas, Mara, Romero, Antonio, Lasa, Inigo, Bou, German |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 56 Num. 12 (pages 6256 to 6266) |
| DOI | https://doi.org/10.1128/aac.01085-12 |
Expression of OXA-Type and SFO-1 beta-Lactamases Induces Changes in Peptidoglycan Composition and Affects Bacterial Fitness
| Authors | Fernandez, Ana, Perez, Astrid, Ayala, Juan A., Mallo, Susana, Rumbo-Feal, Soraya, Tomas, Maria, Margarita Poza, Bou, German |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 56 Num. 4 (pages 1877 to 1884) |
| DOI | https://doi.org/10.1128/aac.05402-11 |
Short communication: A comparative analysis of recombinant chymosins
| Authors | Vallejo, J. A., Ageitos, J. M., Poza, M., Villa, T. G. |
| Journal | JOURNAL OF DAIRY SCIENCE Vol. 95 Num. 2 (pages 609 to 613) |
| DOI | https://doi.org/10.3168/jds.2011-4445 |
Emergence in Spain of a Multidrug-Resistant Enterobacter cloacae Clinical Isolate Producing SFO-1 Extended-Spectrum beta-Lactamase
| Authors | Ana Fernandez, Maria Jose Pereira, Jose Manuel Suarez, Margarita Poza, Mercedes Trevino, Pilar Villalon, Juan Antonio Saez Nieto, Benito Jose Regueiro, Rosa Villanueva, Germán Bou |
| Journal | JOURNAL OF CLINICAL MICROBIOLOGY Vol. 49 Num. 3 (pages 822 to 828) |
Proteomic and Functional Analyses Reveal a Unique Lifestyle for Acinetobacter baumannii Biofilms and a Key Role for Histidine Metabolism
| Authors | Cabral, Maria P., Soares, Nelson C., Aranda, Jesus, Parreira, Jose R., Rumbo, Carlos, Margarita Poza, Valle, Jaione, Calamia, Valentina, Lasa, Inigo, Bou, German |
| Journal | JOURNAL OF PROTEOME RESEARCH Vol. 10 Num. 8 (pages 3399 to 3417) |
| DOI | https://doi.org/10.1021/pr101299j |
Expression of a yeast polygalacturonase gene in Arabidopsis thaliana
| Authors | M. Prieto Alcedo, P. Veiga Crespo, M. Poza, Carmen Coronado Carvajal, I. Zarra, T. G. Villa |
| Journal | BIOLOGIA PLANTARUM Vol. 55 Num. 2 (pages 349 to 352) |
Horizontal Transfer of the OXA-24 Carbapenemase Gene via Outer Membrane Vesicles: a New Mechanism of Dissemination of Carbapenem Resistance Genes in Acinetobacter baumannii
| Authors | Carlos Rumbo, Esteban Fernandez Moreira, Maria Merino, Margarita Poza, Jose Antonio Mendez, Nelson C. Soares, Alejandro Mosquera, Fernando Chaves, Germán Bou |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 55 Num. 7 (pages 3084 to 3090) |
Multidrug-Resistant Acinetobacter baumannii Harboring OXA-24 Carbapenemase, Spain
| Authors | Joshi Acosta, Maria Merino, Esther Viedma, Margarita Poza, Francisca Sanz, Joaquin R. Otero, Fernando Chaves, Germán Bou |
| Journal | EMERGING INFECTIOUS DISEASES Vol. 17 Num. 6 (pages 1064 to 1067) |
Role of changes in the L3 loop of the active site in the evolution of enzymatic activity of VIM-type metallo-beta-lactamases - authors¿ response
| Authors | Maria Merino, Francisco J. Perez Llarena, Frederic Kerff, Margarita Poza, Susana Mallo, Soraya Rumbo-Feal, Alejandro Beceiro, Carlos Juan, Antonio Oliver, Germán Bou |
| Journal | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Vol. 66 Num. 3 (pages 686 to 686) |
A rapid and simple method for constructing stable mutants of Acinetobacter baumannii
| Authors | Aranda, Jesus, Margarita Poza, Pardo, Belen G., Rumbo, Soraya, Rumbo, Carlos, Parreira, Jose R., Rodriguez-Velo, Patricia, Bou, German |
| Journal | BMC MICROBIOLOGY Vol. 10 |
| DOI | https://doi.org/10.1186/1471-2180-10-279 |
OXA-24 Carbapenemase Gene Flanked by XerC/XerD-Like Recombination Sites in Different Plasmids from Different Acinetobacter Species Isolated during a Nosocomial Outbreak
| Authors | Merino, Maria, Acosta, Joshi, Margarita Poza, Sanz, Francisca, Beceiro, Alejandro, Chaves, Fernando, Bou, German |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 54 Num. 6 (pages 2724 to 2727) |
| DOI | https://doi.org/10.1128/aac.01674-09 |
Cloning and Expression of Buffalo Active Chymosin in Pichia pastoris
| Authors | Andres Vallejo, Juan, Manuel Ageitos, Jose, Margarita Poza, Villa, Tomas G. |
| Journal | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Vol. 56 Num. 22 (pages 10606 to 10610) |
| DOI | https://doi.org/10.1021/jf802339e |
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate
| Authors | Perez, Astrid, Canle, Delia, Latasa, Cristina, Margarita Poza, Beceiro, Alejandro, Tomas, Maria del Mar, Fernandez, Ana, Mallo, Susana, Perez, Sonia, Molina, Francisca, Villanueva, Rosa, Lasa, Inigo, Bou, German |
| Journal | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Vol. 51 Num. 9 (pages 3247 to 3253) |
| DOI | https://doi.org/10.1128/aac.00072-07 |
Purification and characterization of a milk-clotting protease from Bacillus licheniformis strain USC13
| Authors | Ageitos, J. M., Vallejo, J. A., Sestelo, A. B. F., Poza, M., Villa, T. G. |
| Journal | JOURNAL OF APPLIED MICROBIOLOGY Vol. 103 Num. 6 (pages 2205 to 2213) |
| DOI | https://doi.org/10.1111/j.1365-2672.2007.03460.x |
Cloning and expression of the XPR2 gene from Yarrowia lipolytica in Pichia pastoris
| Authors | Poza, M., Sestelo, A. B. F., Ageitos, J. M., Vallejo, J. A., Veiga-Crespo, P., Villa, T. G. |
| Journal | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Vol. 55 Num. 10 (pages 3944 to 3948) |
| DOI | https://doi.org/10.1021/jf0633894 |
Putative ancient microorganisms from amber nuggets
| Authors | Veiga-Crespo, Patricia, Blasco, Lucia, Margarita Poza, Villa, Tomas G. |
| Journal | International Microbiology Vol. 10 Num. 2 (pages 117 to 122) |
| DOI | https://doi.org/10.2436/20.1501.01.17 |
Enzybiotics: A look to the future, recalling the past
| Authors | Veiga-Crespo, Patricia, Ageitos, Jose Manuel, Margarita Poza, Villa, Tomas G. |
| Journal | JOURNAL OF PHARMACEUTICAL SCIENCES Vol. 96 Num. 8 (pages 1917 to 1924) |
| DOI | https://doi.org/10.1002/jps.20853 |
Fluorescein thiocarbamoyl-kappa-casein assay for the specific testing of milk-clotting proteases
| Authors | Ageitos, J. M., Vallejo, J. A., Poza, M., Villa, T. G. |
| Journal | JOURNAL OF DAIRY SCIENCE Vol. 89 Num. 10 (pages 3770 to 3777) |
| DOI | https://doi.org/10.3168/jds.s0022-0302(06)72418-3 |
Hydrolases as markers of wine aging
| Authors | Blasco, L., Veiga-Crespo, P., Poza, M., Villa, T. G. |
| Journal | WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY Vol. 22 Num. 11 (pages 1229 to 1233) |
| DOI | https://doi.org/10.1007/s11274-006-9165-x |
Proposal of a method for the genetic transformation of Gordonia jacobaea
| Authors | Veiga-Crespo, P, Feijoo-Siota, L, de Miguel, T, Poza, M, Villa, TG |
| Journal | JOURNAL OF APPLIED MICROBIOLOGY Vol. 100 Num. 3 (pages 608 to 614) |
| DOI | https://doi.org/10.1111/j.1365-2672.2005.02806.x |
Influence of culture conditions of Gordonia jacobaea MV-26 on canthaxanthin production
| Authors | Veiga-Crespo, P, Blasco, L, dos Santos, FR, Poza, M, Villa, TG |
| Journal | International Microbiology Vol. 8 Num. 1 (pages 55 to 58) |
Cloning and expression of clt genes encoding milk-clotting proteases from Myxococcus xanthus 422
| Authors | Poza, M, Prieto-Alcedo, M, Sieiro, C, Villa, TG |
| Journal | APPLIED AND ENVIRONMENTAL MICROBIOLOGY Vol. 70 Num. 10 (pages 6337 to 6341) |
| DOI | https://doi.org/10.1128/aem.70.10.6337-6341.2004 |
beta-Glucosidase activity in a Lactobacillus plantarum wine strain
| Authors | Sestelo, ABF, Poza, M, Villa, TG |
| Journal | WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY Vol. 20 Num. 6 (pages 633 to 637) |
| DOI | https://doi.org/10.1023/b:wibi.0000043195.80695.17 |
Ancient genes of Saccharomyces cerevisiae
| Authors | Veiga-Crespo, P, Poza, M, Prieto-Alcedo, M, Villa, TG |
| Journal | MICROBIOLOGY-UK Vol. 150 Num. 7 (pages 2221 to 2227) |
| DOI | https://doi.org/10.1099/mic.0.27000-0 |
Enzymes as potential markers of wine aging
| Authors | Zamuz, S, Sestelo, ABF, Poza, M, Villa, TG |
| Journal | JOURNAL OF THE INSTITUTE OF BREWING Vol. 110 Num. 3 (pages 220 to 226) |
Paenibacillus favisporus sp nov., a xylanolytic bacterium isolated from cow faeces
| Authors | E Velázquez, T de Miguel, M Poza, R Rivas, Roselló-Mora R, TG Villa |
| Journal | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY Vol. 54 (pages 59 to 64) |
Genetic basis of microbial carotenogenesis
| Authors | Sieiro, C, Poza, M, de Miguel, T, Villa, TG |
| Journal | International Microbiology Vol. 6 Num. 1 (pages 11 to 16) |
| DOI | https://doi.org/10.1007/s10123-003-0097-0 |
Production and characterization of the milk-clotting protease of Myxococcus xanthus strain 422
| Authors | Poza, M, Sieiro, C, Carreira, L, Barros-Velazquez, J, Villa, TG |
| Journal | JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY Vol. 30 Num. 12 (pages 691 to 698) |
| DOI | https://doi.org/10.1007/s10295-003-0100-y |
Heterologous expression of the Saccharomyces cerevisiae PGU1 gene in Schizosaccharomyces pombe yields an enzyme with more desirable properties for the food industry
| Authors | Sieiro, C, Poza, A, Guillermo Vilanova, Villa, TG |
| Journal | APPLIED AND ENVIRONMENTAL MICROBIOLOGY Vol. 69 Num. 3 (pages 1861 to 1865) |
| DOI | https://doi.org/10.1128/aem.69.3.1861-1865.2003 |
Analysis of canthaxanthin and related pigments from Gordonia jacobaea mutants
| Authors | de Miguel, T, Sieiro, C, Poza, M, Villa, TG |
| Journal | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY Vol. 49 Num. 3 (pages 1200 to 1202) |
| DOI | https://doi.org/10.1021/jf001169z |
Characterization of a broad pH range protease of Candida caseinolytica
| Authors | Poza, M, de Miguel, T, Sieiro, C, Villa, TG |
| Journal | JOURNAL OF APPLIED MICROBIOLOGY Vol. 91 Num. 5 (pages 916 to 921) |
| DOI | https://doi.org/10.1046/j.1365-2672.2001.01458.x |
Isolation and taxonomic study of a new canthaxanthin-containing bacterium, Gordonia jacobaea MV-1 sp. nov.
| Authors | T de Miguel, C Sieiro, M Poza, TG Villa |
| Journal | International Microbiology Vol. 3 (pages 107 to 111) |
Industrial applications of microbial proteases and genetic engineering
| Authors | M Poza,JM Ageitos,JA Vallejo,T de Miguel,P Veiga-Crespo,TG Villa |
| Book |
Hot Spots in Applied Microbiology Publishing: Research Signpost 37/ 661 (2), Fort P. O. Trivandrium-695023, Kerala . ISBN: 81-308-0144-2 |
| Pages | From 91 to 125 |
Enzybiotics; old friends for new therapeutic tools
| Authors | P Veiga-Crespo,L Blasco,JA Vallejo,M Poza,TG Villa |
| Book |
Hot Spots in Applied Microbiology Publishing: Research Signpost 37/ 661 (2), Fort P. O. Trivandrium-695023, Kerala . ISBN: 81-308-0144-2 |
| Pages | From 217 to 240 |
Hyperthermophilic enzymes of industrial relevance
| Authors | T de Miguel,M Poza,P Veiga-Crespo,TG Villa |
| Book |
Microorganisms for industrial enzymes and biocontrol Publishing: Research Signpost 37/ 661 (2), Fort P. O. Trivandrium-695023, Kerala . ISBN: 81-308-0040-3 |
| Pages | From 45 to 58 |
A quarter of a century in microbial xanthophylls
| Authors | C Sieiro,M Poza,TG Villa |
| Book |
Useful microorganisms for health care, foods and enzyme production Publishing: Research Signpost 37/ 661 (2), Fort P. O. Trivandrium-695023, Kerala . ISBN: 81-7736-161-9 |
| Pages | From 85 to 101 |
Emergence of Carbapenemase Genes in Gram-Negative Bacteria Isolated from the Wastewater Treatment Plant in A Coruña, Spain
| Author | Mohammed Nasser Mohammed Ali |
| Director/s | Margarita Poza Domínguez; Juan Andrés Vallejo Vidal |
| Scope | Facultad de Ciencias |
| Qualification | Sobresaliente Cum Laude |
COVIDBENS: epidemiología de COVID-19 basada en aguas residuales de A Coruña
| Author | Noelia Trigo Tasende |
| Director/s | Ricardo José Cao Abad; Susana Ladra González; Margarita Poza Domínguez |
| Scope | Facultad de Ciencias |
| Qualification | Sobresaliente Cum Laude |
Microbioma y cáncer colorrectal: translocación de bacterias orales al intestino y búsqueda de potenciales biomarcadores
| Author | Kelly Conde Pérez |
| Director/s | Margarita Poza Domínguez; Juan Andrés Vallejo Vidal |
| Scope | Facultad de Ciencias |
| Qualification | Sobresaliente Cum Laude |
Transcriptional analysis reveals new factors involved in the biofilm formation ability of Acinetobacter baumannii
| Author | Soraya Rumbo Feal |
| Director/s | Germán Bou Arevalo; Margarita Poza Domínguez |
| Scope | Facultad de Ciencias de la Salud |
| Qualification | Sobresaliente Cum Laude |
Caracterización de nuevos factores de virulencia del patógeno nosocomial Acinetobacter baumannii
| Author | Laura Alvarez Fraga |
| Director/s | Alejandro Beceiro Casas;Germán Bou Arevalo; Margarita Poza Domínguez |
| Scope | Facultad de Ciencias |
| Qualification | Sobresaliente Cum Laude |
Esutido de un brote epidémico causado por distintas cepas de Acinetobacter baumannii multirresistente. Estudio de epidemicidad y virulencia
| Author | María Merino Carballeira |
| Director/s | Germán Bou Arevalo; Margarita Poza Domínguez |
| Scope | Medicina |
| Qualification | Sobresaliente Cum Laude |
Implicación de la bomba de expulsión AcrAB-TolC en la resistencia antimicrobianos y en la virulencia del microorganismo patógeno Enterobacter Cloacae
| Author | Ástrid Pérez Gómez |
| Director/s | Margarita Poza Dominguez; Germán Bou Arevalo |
| Scope | Biología Celular y Molecular |
| Qualification | Apto Cum Laude |
Purificación, caracterización y expresión heteróloga de la proteasa Epr de Bacillus licheniformis
| Author | José Manuel Ageitos Martínez |
| Director/s | Margarita Poza Domínguez Tomás G. Villa |
| Scope | Universidade de Santiago de Compostela |
| Qualification | Sobresaliente Cum Laude |
Clonación y expresión de la quimosina de Bubalus arnee bubalis en E. coli y levaduras
| Author | Juan Andrés Vallejo Vidal |
| Director/s | Margarita Poza Domínguez Tomás G Villa |
| Scope | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA |
| Qualification | Sobresaliente Cum Laude |
Estudio molecular, análisis de la pigmentación y aplicabilidad industrial de Gordonia jacobaea
| Author | Patricia Veiga Crespo |
| Director/s | Margarita Poza Domínguez Tomás G Villa |
| Scope | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA |
| Qualification | Sobresaliente Cum Laude |
Clonación y caracterización de genes codificantes para proteasas de uso industrial a partir de Candida caseinolytica, Yarrowia lipolytica y Bacillus licheniformis
| Author | Ana Belén Fernández Sestelo |
| Director/s | Margarita Poza Domínguez Tomás G Villa |
| Scope | UNIVERSIDAD DE SANTIAGO DE COMPOSTELA |
| Qualification | Sobresaliente Cum Laude |