Grupo de Investigación en Nanotoxicología y Toxicología Genética (NANOTOXGEN)

Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models

Iron (II)-cyclopentadienyl compounds are cytotoxic against colon adenocarcinoma cell lines: Ethylenebis (diphenylphosphane) vs. triphenylphosphane

Solution State Cooperative Luminescence Upconversion in Molecular Ytterbium Dimers

Polymer-Supported Oxidovanadium(IV) Complexes and Their Catalytic Applications in One-Pot Multicomponent Reactions Producing Biologically Active 2,4,5-Trisubstituted-1H-imidazoles

Measuring DNA modifications with the comet assay: a compendium of protocols

Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos

Trinuclear dioxidomolybdenum (VI) complexes derived from benzene-1, 3, 5-tricarbohydrazide and study of the catalytic activity

Inter-laboratory variation in measurement of DNA damage by the alkaline comet assay in the hCOMET ring trial

DNA strand break levels in cryopreserved mononuclear blood cell lines measured by the alkaline comet assay: results from the hCOMET ring trial

Cytotoxic Effects of Zinc Oxide Nanoparticles on Human Glial Cells

Association of Torquetenovirus viremia with physical frailty and cognitive impairment in three independent European cohorts

Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results

Multiparametric In Vitro Genotoxicity Assessment of Different Variants of Amorphous Silica Nanomaterials in Rat Alveolar Epithelial Cells.

Catalytic Potential of Pyrazolone Based Dioxidomolybdenum(VI) Complexes for Multicomponent Biginelli Reactions, Epoxidation of Olefins and Oxidative Bromination of Phenol Derivatives

First iron (II) organometallic compound acting as ABCB1 inhibitor

Long-term cryopreservation of potassium bromate positive assay controls for measurement of oxidatively damaged DNA by the Fpg-modified comet assay: results from the hCOMET ring trial

Ruthenium (II) polypyridyl complexes with benzothiophene and benzimidazole derivatives: Synthesis, antitumor activity, solution studies and biospeciation

A pooled analysis of molecular epidemiological studies on modulation of DNA repair by host factors

Molecular structure and biological activities of 4-thiazolidinone derivatives: a combined theoretical and experimental study

Study on the effects of exposure to zinc oxide nanoparticles and zinc sulphate in zebrafish (Danio rerio) embryos and larvae

Design, Synthesis, biological activity and structural analysis of novel des-C-ring and aromatic-D-ring analogues of 1a,25-dihydroxyvitamin D3

Cytotoxicity and Genotoxicity of Nanomaterials.

Relationship between DNA damage measured by the comet-assay and cognitive function

Suitability of salivary leucocytes to assess DNA repair ability in human biomonitoring studies by the challenge-comet assay

Substituent Controlled Synthesis of Dioxidomolybdenum(VI) Complexes of N,N,N¿,N¿-Tetrakis(2-Hydroxyl-3,5-Disubstitutedbenzyl)-1,2-Diaminoethane, Their Trans-Metalation to Oxidovanadium(V) Complexes and Biocatalytic Applications

Relationship between structure and cytotoxicity of vanadium and molybdenum complexes with pyridoxal derived ligands

Synthesis, Characterization and Biomimetic Activity of Heterogenized Dioxidomolybdenum(VI) and Analogous Homogeneous Complexes

Amine-functionalized titanium dioxide supported dioxidomolybdenum(VI) complexes as functional model for phenoxazinone synthase enzyme

Mononuclear/Binuclear [VIVO]/[VVO2] Complexes Derived from 1,3- Diaminoguanidine and Their Catalytic Application for the Oxidation of Benzoin via Oxygen Atom Transfer

The Centennial Collection of VDR Ligands: Metabolites, Analogs, Hybrids and Non-Secosteroidal Ligands

From trihalomethanes chronic daily intake through multiple exposure routes to cancer and non-cancer health risk assessment: Evidence from public Portuguese indoor swimming pools facilities using a probabilistic approach

Influenceof CoordinationGeometryon the Ring Openingof Benzoxazine:Oxidovanadium(V),Dioxidomolybdenum(VI)and Dioxidotungsten(VI)Complexesof BenzoxazineBasedLigandsand their BioInspiredCatalyticApplications

Biscoumarin¿pyrimidine conjugates as potent anticancer agents and binding mechanism of hit candidate with human serum albumin

Genetic characterization of wild, broodstock and seed samples of Polititapes rhomboides (Bivalvia: Veneridae): Implications for hatchery seed production

Selective Bromination of ß-Positions of Porphyrin by Self-Catalytic Behaviour of VOTPP: Facile Synthesis, Electrochemical Redox Properties and Catalytic Application

Oxidovanadium (IV/V) complexes bound with a ONS donor backbone: The search for therapeutic versatility in one class of compounds

DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death

Genomic instability as a main driving factor of unsuccessful ageing: potential for translating the use of micronuclei into clinical practice

The hCOMET project: international database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders

Salivary leucocytes as suitable biomatrix for the comet assay in human biomonitoring studies

Innovative three-step microwave-promoted synthesis of N-propargyltetrahydroquinoline and 1,2,3-triazole derivatives as a potential factor Xa (FXa) inhibitors: drug design, synthesis and biological evaluation

Therapeutic potential of vanadium complexes with 1,10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells

Collection and storage of human white blood cells for analysis of DNA damage and repair activity using the comet assay in molecular epidemiology studies

Exploring early detection of frailty syndrome in older adults: evaluation of oxi-immune markers, clinical parameters and modifiable risk factors

Suitability of the in vitro cytokinesis-block micronucleus test for genotoxicity assessment of TiO2 nanoparticles on SH-SY5Y cells

Applicability of flow cytometry gH2AX assay in population studies: suitability of fresh and frozen whole blood samples

5-Fluorouracil (5-FU)-based Aza-Michael addition product: A selective carbonic anhydrase IX inhibitor

Synthesis, characterization and DFT studies of novel -CH2- capped and non-capped salan complexes

Salivary leucocytes as in vitro model to evaluate nanoparticle-induced DNA damage

Design, Synthesis, Evaluation and Structure of Allenic 1¿,25-Dihydroxyvitamin D3 Analogs with Locked Mobility at C-17

Unusual chemistry of Cu(II) salan complexes: Synthesis, characterization and superoxide dismutase activity

Association of inflammatory mediators with frailty status in older adults: results from a systematic review and meta-analysis

Identification of morpholine based hydroxylamine analogues: Selective inhibitors of MARK4/Par-1d causing cancer cell death through apoptosis

Microwave-mediated synthesis of N-allyl/propargyl derivatives: enzymatic analysis as a potential factor Xa (FXa) inhibitor, theoretical and computational molecular docking

A new family of iron(II)-cyclopentadienyl compounds shows strong activity against colorectal and triple negative breast cancer cells

Genotoxicity of TiO2 nanoparticles in four different human cell lines (A549, HEPG2, A172 and SH-SY5Y)

Frailty syndrome, biomarkers and environmental factors - a pilot study

Minimum Information for Reporting Comet Assay (MIRCA) procedures and results

The impact of nanotechnology in the current universal COVID-19 crisis. Let's not forget nanosafety!

Moving towards common data elements and core outcome measures in frailty research

Trinuclear vanadium(iv) and vanadium(v) complexes derived from 2,4,6-triacetylphloroglucinol and study of their peroxidase mimicking activity

Low vitamin D levels and frailty status in older adults: a systematic review and meta-analysis

Genetic variability in Ruditapes decussatus clam combined with Perkinsus infection level to support founder population selection for a breeding program

Trinuclear cis-dioxidomolybdenum(VI) complexes of compartmental C3 symmetric ligands: Synthesis, characterization, DFT study and catalytic application for hydropyridines (Hps) via the Hantzsch reaction

Expanded usage of the Challenge-Comet assay as a DNA repair biomarker in human populations: protocols for fresh and cryopreserved blood samples, and for different challenge agents

Potassium bromate as positive assay control for the Fpg-modified comet assay

4,6-diacetyl resorcinol based vanadium(V) complexes: reactivity and catalytic applications

Optimization of the harvesting and freezing conditions of human cell lines for DNA damage analysis by the alkaline Comet assay

Vitamin D and Its Synthetic Analogs

Evaluation of cytotoxicity and genotoxicity induced by oleic acid-coated iron oxide nanoparticles in human astrocytes

Vanadium(V) and Molybdenum(VI) complexes containing ONO tridentate Schiff Bases and their applications as catalysts for oxidative bromination of phenols

Exploring genetic outcomes as frailty biomarkers

Synthesis, characterization and catalytic activity of dioxidouranium(VI) complexes of ONNO tetradentate Mannich bases

Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect

Synthesis, Characterization, Molecular Docking, and Anticancer Evaluatin of 4-Thiazolidinone Analogues

Dioxidomolybdenum(VI) and dioxidouranium(VI) complexes as functional mimic of haloperoxidases catalytic activity in presence of H2O2-KBr-HClO4

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand

Assessment of oxidative damage induced by iron oxide nanoparticles on different nervous system cells

Serum corticol but not oxidative biomarkers are related to Frailty: results of a cross-sectional study in Spanish older adults

Mechanistic insights for the transprotection of tertiary amines with Boc2O via charged carbamates: access to both enantiomers of 2-azanorbornane-3-exo-carboxylic acids

Synthesis, structural and biological activity of N-substitutd 2-methyl-4-/5-nitroimidazole derivatives

Coumarin tethered cyclic imides as efficacious gluose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin

Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on Caco-2 and HT29-MTX intestinal cells

Occupational exposure to formaldehyde and early biomarkers of cancer risk, immunotoxicity and susceptibility

Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists

Stereoselective synthesis of 25S,26-dihydroxyvitamin D3

Total synthesis of 1¿,25-dihydroxyvitamin D3 analogs modified at the side chain and D-ring

RNA-Seq Analysis for Assessing the Early Response to DSP Toxins in Mytilus galloprovincialis Digestive Gland and Gill

Frailty in older adults is associated with plasma concentrations of inflammatory mediators but not with lymphocyte subpopulations

An alternative method for rapid and specific authentication of four European Donax species, including D. trunculus a commercially-important bivalve

Mitochondrial DNA analyses of Donax trunculus (Mollusca: Bivalvia) population structure in the Iberian Peninsula, a bivalve with high commercial importance

Frailty syndrome and genomic instability in older adults. Suitability of the Cytome Micronucleus Assay as a diagnostic tool

Design, synthesis and biological evaluation of quinazolin-4(3H)-one Schiff base conjugates as potential antiamoebic agents

Sequence characterization of the 5S ribosomal DNA and the internal transcribed spacer (ITS) region in four European Donax species (Bivalvia: Donacidae)

Stereoselective Palladium¿Catalyzed Approach to Vitamin D3 Derivatives in Protic Medium

Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes

Oxygen atom transfer between DMSO and benzoin catalyzed by cis-dioxidomolybdenum(VI) complexes of tetradentate Mannich bases

Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agentes: their DNA cleavage ability and BSA interaction study

Novel Ruthenium methyl cyclopentadienyl complex bearing a bibyridine perfluorinated ligand shows strong activity towards colorectal cancer cells

Synthesis of Side-Chain Locked Analogs of 1¿,25-Dihydroxyvitamin D3 Bearing a C17 Methyl Group

Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents, targetin human carbonic anhydrase IX

Methyl-cyclopentadienyl ruthenium compounds with 2.2¿-bipyridine derivatives display strong anticancer activity and multidrug resistence potential

Neurotoxicity assessment of oleic acid-coated iron oxide nanoparticles in SH-SY5Y cells

Trinuclear Dioxidomolybdenum(VI) Complexes of Tritopic Phloroglucinol-Based Ligands and Their Catalytic Applications for the Selective Epoxidation of Olefins

Comparative study of human neuronal and glial cell sensitivity for in vitro neurogenotoxicity testing

New iron cyclopentadienyl complexes bearing different phosphane co-ligands: structural factors vs. cytotoxicity

Effects of Degree of Urbanization and Lifetime Longest-Held Occupation on Cognitive Impairment Prevalence in an Older Spanish Population

New Cu(II) complexes with pyrazolyl derived Schiff base ligands: synthesis and biological evaluation

First complete female mitochondrial genome in four bivalve species genus Donax and their phylogenetic relationships within the Veneroida order

Synthesis, sterochemistry determination, pharmacological studies and quantum chemical analyses of bisthiazolidinone derivative

Synthesis, characterization, citotoxicity, cell cycle analysis of 3-(-4-methoxyphenyl)-1-(pyridin-2-ylmethyl)thiourea and quantum chemical analyses

Microsatellite variation in Donax trunculus from the Iberian Peninsula, with particular attention to Galician estuaries (NW Spain)

Immune biomarkers in older adults: Role of physical activity

1ß,25-Dihydroxyvitamin D3: A new vitamin D metabolite in human serum.

Total synthesis of 1¿,25-dihydroxyvitamin D3 (calcitriol) through a Si-assisted allylic substitution

Transcriptional and biochemical analysis of antioxidant enzymes in the mussel Mytilus galloprovincialis during experimental exposures to the toxic dinoflagellate Prorocentrum lima

Oxidative stress, genomic features and DNA repair in frail elderly: A systematic review.

Phloroglucinol and resorcinol based mononuclear dixoidomolybdenum(VI) complexes: synthesis, characterization and catalytic epoxidation

A new approach to 19-nor-A-ring phosphine oxide for the convergent synthesis of 19-nor-calcitriol

Frailty status in older adults is related to alterations in indoleamine 2,3-dioxygenase 1 and guanosine triphosphate cyclohydrolase I enzymatic pathways

Solution behaviour and catalytic potential towards oxidation of dopamine by oxidovanadium(V) complexes of tripodal tetradentate ligands

Is salivary chromogranin A a valid psychological stress biomarker during sensory stimulation in people with advanced dementia?

Bis{cis[MoO2]}complexes of 4,6-diacetyl resorcinol bis(hydrazone) and their catalytic application for the three compounds dinaymi assembly via Hantzsch reaction

Molybdenum complexes with a u-O{MO2}2 core: their synthesis, crystal structure and application as catalysts for the oxidation of bicyclic alcohols using N-based additives

Computational and experimental studies of 4-thiazolidinone-cyclopropyl hybrid

Genetic diversity and population genetic analysis of Donax vittatus (Mollusca: Bivalvia) and phylogeny of the genus with mitochondrial and nuclear markers

Synthesis and biological evaluation of 4-(2-(dimethylamino)ethoxy) benzohydrazide derivatives as inhibitors of Entamoeba hystolitica

In vitro toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells

Study of temperature dependent three component dynamic covalent assembly via Hantzsch reaction catalyzed by dioxido- and oxidoperoxidomolybdenum(VI) complexes under solvent free conditions

Theoretical and exprimental studies of 3B-acetoxy-5a-cholestan-6-one oxime

Vanadium complexes derived from acetyl pyrazolone and hydrazides: Structure, reactivity, peroxidase mimicry and efficient catalityc activity for the oxidation fo 1-phenylethanol

Oxidoperoxidotungsten(VI) and dioxidotungsten(VI) complexes catalyzed oxidative bromination of thymol in presence of H2O2-KBr-HClO4

Thienopyrimidine sulphonamide hybrids: design, synthesis, antiprotozoal activity and molecular docking studies

Synthesis, characterization, reactivity, catalityc activity, and antiamoebic activity of vanadium(V) complexes of ICL670(Deferasirox) and related ligand

Vitamin D receptor 2016: novel ligands and structural insights.

Dioxidomolybdenum(VI) complexes of tripodal tetradentate ligands for catalytic oxygen atom transfer between benzoin and dimethyl sulfoxide and for oxidation of pyragallol

Efectos celulares y moleculares de nanopartículas de magnetita en células neuronales humanas

Effects of exposure to oil spills on human health: Updated review

Stereoselective synthesis of 1ß,25-Dihydroxyvitamin D3 and its 26,27-hexadeuterated derivative.

Carborane-based design of a potent vitamin Dreceptor agonist

Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis

Are iron oxide nanoparticles safe? Current knowledge and future perspectives

n6-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2¿-bipyridine and its derivatives: solution speciation and kinetic behaviour

Health determinants of nutritional status in community-dwelling older population: the VERISAÚDE study

Characterization of mussel H2A.Z.2: a new H2A.Z variant preferentially expressed in germinal tissues from Mytilus

Synthesis, antiamoebic and molecular docking studies of furan-thiazolidinone hybrids

Vanadium(IV and V) complexes of pyrazolone based ligands: synthesis, structural caracterización and catalytic applications

yH2AX Assay as DNA Damage Biomarker for Human Population Studies: Defining Experimental Conditions

Identification of four Donax species by PCR-RFLP analysis of cytochrome c oxidase subunit I (COI)

Mimicking peroxidase activity by a polymer-supported oxidovanadium(IV) Schiff base complex derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane.

Chloroquinoline-acetamide hybrids: a promising series of potential antiprotozoal agents

Palladium(II) complexes of OS donor N-(di(butyl/phenyl)carbamothioyl)benzamide and their antiamoebic activity

Quantitative analytical method to evaluate the metabolism of vitamin D

In vitro toxicity screening of silica-coated superparamagnetic iron oxide nanoparticles in glial cells

Oxidation of secondary alcohols by conventional and microwave-assisted methods using molybdenum complexes of ONO donor ligands

Unbiased high-throughput characterization of mussel transcriptomic responses to sublethal concentrations of the biotoxin okadaic acid

Lymphocyte subsets in a population of non-frail elder individuals

Oxidovanadium(IV) and dioxidovanadium (V) complexes of hydrazones of 2-benzoylpyridine and their catalytic applications

Synthesis, characterization and antiamoebic activity of chalcones bearing N-substituted ethanamine tail

Pit-1 inhibits BRCA1 and sensitizes human breast tumors to cisplatin and vitamin D treatment

Silica-coated iron oxide nanoparticles do not induce DNA double strand breaks or aneugenicity sin SHSY5Y neuronal cells

Liquid phase versus microwave assisted selective oxidation of volatile organic compounds involving dioxidomolybdenum(VI) and oxidoperoxidomolybdenum(VI) complexes as catalysts in the presence/absence of an N-based additive

Oxidative bromination of monoterpene (thymol) using dioxidomolybdenum(VI) complexes of hydrazones of 8-formyl-7-hydroxy-4-methylcoumarin

The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds

Effects of Iron Oxide Nanoparticles: Cytotoxicity, Genotoxicity, Developmental Toxicity, and Neurotoxicity

In Vitro Analysis of Early Genotoxic and Cytotoxic Efffects of Okadaic Acid in Different Cell Types of the Mussel Mytilus galloprovincialis

Catalytic oxidation of secondaryy alcohols by molybdenum complexes derived from 4-acyl pyrazolone in presence and absence of an N-based additive: Conventional versus microwave assisted method.

Vanadium(v) complexes of a tripodal ligand, their characterisation and biological implications

Catalytic oxidation of internal and terminal alkenes by oxidoperoxidomolybdenum(VI) and dioxidomolybdenum(VI) complexes

Synthesis and characterization of di-u-oxidovanadium(V), oxidoperoxido-vanadium(V) and polymer supported dioxidovanadium(V) complexes and catalytic oxidation of isoeugenol

Oxidative stress induced by silica-coated iron oxide nanoparticles in SHSY5Y neuronal cells

Effect of N-based additive on the optimization of liquid phase oxidation of bicyclic, cyclic and aromatic alcohols catalyzed by dioxidomolybdenum(VI) and oxidoperoxidomolybdenum(VI) complexes

In vitro cytotoxicity of superparamagnetic iron oxide nanoparticles on neuronal and glial cells. Evaluation of nanoparticle interference with viability tests

Lymphocyte Subsets in a Population of Nonfrail Elderly Individuals

Polystyrene bound dioxidovanadium(V) complexes of 2-acetylpyridine derived ligands for catalytic oxidations

Polymer and non-polymer-grafted dioxidomolybdenum(VI) complexes having ONO donor ligand and their catalytic activities for the oxidative bromination of organic substrates

An Efficient Convergent Synthesis of 1a,25-dihydroxy-3-epi-vitamin D2

Endo-benzonorbornen-2-ol as an efficient non-natural chiral auxiliary in the asymmetric aza-Diels-Alder reactions between cyclopentadiene and (1-phenylethyl)iminoacetates

Characterization of nineteen microsatellite markers and development of multiplex PCRs for the wedge clam Donax trunculus (Mollusca: Bivalvia)

Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin

Folow-up study of genotoxic effects in individuals exposed to oil from the tanker Prestige, seven years after the accident

Synthesis of nonadeuterated 1a,25-dihydroxyvitamin D2

Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD

AvaliaÇao in vitro da neurotoxicidade de nanopartículas de magnetite revestidas por sílica

Synthesis, crystal structures, antimicrobial activities, and DFT calculations of two new azido nickel(II) complexes

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories

Chiral N(H)-tBu and N(H)-Ad NiII complexes of Glycine Schiff Bases: Deduction of a Mode of Kinetic Diastereoselectivity

Synthesis of 4'-(2-ferrocenyl)-2,2':6'2'' -terpyridine: Characterization and antiprotozoal activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes

Hydroxyquinoline derived vanadium(IV and V) and copper(II) complexes as potential anti-tuberculosis and anti-tumor agents

Synthesis, characterization and catalytic activity of dioxodomolybdenum(VI) complexes of tribasic pentadentate ligands.

A Chiral N(H)-tBu and N(H)-Ad NiII Complexes of Glycine Schiff Bases:Deduction of a Mode of Kinetic Diastereoselectivity

Is organic farming safer to farmers' health? A comparison between organic and traditional farming

Synthesis, characterization and catalytic activity of dioxodomolybdenum(VI) complexes derived from tribasic ONS donor ligands

Polymer-grafted and neat vanadium(V) complexes as functional mimics of haloperoxidases

CuII-salan compounds: Synthesis, characterization and evaluation of their potential as oxidation catalysts

Okadaic acid meet and greet: an insight into detection methods, response strategies and genotoxic effects in marine invertebrates

Endocrine and immunological parameters in individuals involved in Prestige spill cleanup tasks seven years after the exposure

Geographical variation in shell shape of the pod razor shell Ensis siliqua (Bivalvia:Pharidae)

Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl)quinoline-sulfonamide as hybrid antiprotozoal agents

An ECVAG inter-laboratory validation study of the comet assay:inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells

An Approach to 2,4-Substituted Pyrazolo[1,5-a|pyridines and Pyrazolo[1,5-a|azepines by Ring-Closing Metathesis

Gold-Catalyzed Intramolecular Hydroamination of o-Alkynylbenzyl Carbamates: A Route to Chiral Fluorinated Isoindoline and Isoquinoline Derivatives

Gold catalyzed stereoselective tandem hydroamination¿formal aza-Diels¿Alder reaction of propargylic amino esters

A efficient synthesis of 1a,25-dihydroxy-20-epi-vitamin D3

Synthesis, structural characterization, encapsulation in zeolite Y and catalytic activity of an oxidovanadium(V) complex with a tribasic pentadentate ligand

The marine toxin okadaic acid induces alterations in the expression level of cancer-related genes in human neuronal cells

Effect of okadaic acid on carpet shell clam (Ruditapes decussatus) haemocytes by in vitro exposure and harmful algal bloom simulation assays

Comparative study on effects of two different types of titanium dioxide nanoparticles on human neuronal cells

Synthesis, characterization, reactivity, identification of isomeric species and crystal structure of dinitrosylmolybdenum(0) complexes of 2-(alfa-hydrosyalkyl/aryl)benzimidazole

Daño al sistema nervioso inducido por nanopartículas

Vanadium complexes having [VO]2+, [VO]3+ and [VO2]+ cores with hydrozones of 2,6-diformyl-4-methylpehonol: synthesis, characterization, reactivity and catalytic potential

Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands

Base-Dependent Stereodivergent Intramolecular Aza-Michael Reaction: Asymmetric Synthesis of 1,3-Disubstituted Isoindolines

Okadaic Acid: More than a Diarrheic Toxin

A novel VIVO-pyrimidinone complex: synthesis, solution speciation and human serum protein binding

Neuronal cytotoxicity and genotoxicity induced by zinc oxide nanoparticles

The CHROMAEVALOA Database: A Resource for the Evaluation of Okadaic Acid Contamination in the Marine Environment Based on the Chromatin-Associated Transcriptome of the Mussel Mytilus galloprovincialis IF:4,379 Q1

Chromatin specialization in bivalve molluscs: A leap forward for the evaluation of Okadaic Acid genotoxicity in the marine environment

Metronidazole thiosalicylate conjugates: Synthesis, crystal structure, docking studies and antiamoebic activity

Assessment of immunotoxicity parameters in individuals occupationally exposed to lead

Synthesis, characterization and structure optimization of a series of thiazolidinone derivatives as Entamoeba histolytica inhibitors

Synthesis and Biological Evaluation of 1¿,25-Dihydroxyvitamin D3 Analogues with a Long Side Chain at C12 and Short C17 Side Chain

Amino Alcohol-Derived Reduced Schiff Base VIVO and VV Compounds as Catalysts for Asymmetric Sulfoxidation of Thioanisole with Hydrogen Peroxide

Mn(III) complexes of monoprotic tridentate ONN donor 2-[2-(1H-(benzo[d]imidazol-2-yl)ethylimino)methyl]phenol as a functional mimic of haloperoxidase

Synthesis of (1a)-1,25-Dihydroxyvitamin D3 with a ß-Positioned Seven-Carbon Side Chain at C(12)

Identification of Ensis siliqua Samples and Establishment of the Catch Area Using a Species-Specific Microsatellite Marker

Genotyping an ALAD Polymorphism with Real-Time PCR in Two Populations from the Iberian Peninsula

Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair

Dinuclear MnIII Compounds [{Mn(bpy)(H2O)}2(¿-4-RC6H4COO)2(¿-O)](NO3)2 (R = Me, F, CF3, MeO, tBu): Effect of the R Group on the Magnetic Properties and the Catalase Activity

Aliphatic Dicarboxylate Ligands Assemble Weakly Coupled Molecular Pairs of [MnIII]2 Units

Enantio- and Diastereoselective Organocatalytic ¿-Alkylation of Aldehydes with 3-Substituted 2-(Bromomethyl)acrylates

Isolation of Microsatellite Markers and Analysis of Genetic Diversity Among East Atlantic Populations of the Sword Razor Shell Ensis siliqua: A Tool for Population Management

Inter-laboratory variation in DNA damage using a standard comet assay protocol

Effects of okadaic acid on haemocytes from Mytilus galloprovincialis : A comparasion between field and laboratory studies

Synthesis, characterisation and catalytic activities of manganese(III) complexes of pyridoxal-based ONNO donor tetradenatate ligands

In vivo genotoxicity assessment in rats exposed to Prestige-like oil by inhalation

Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines

Spectroscopic and Structural Characterization of Noninnocent Mixed-Ligand Oxidovanadium(V) Complexes

Design, Synthesis, Evaluation, and Structure of Vitamin D Analogues with Furan Side Chains

Histone H2A (H2A.X and H2A.Z) Variants in Molluscs: Molecular Characterization and Potential Implications For Chromatin Dynamics

Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization

Alterations in metabolism-related genes induced in shsy5y cells by okadaic acid exposure

Identification of the wedge clam Donax trunculus by a simple PCR technique

Intramolecular Michael Reaction of tert-Butylsulfinyl Ketimines: Asymmetric Synthesis of 3-Substituted Indanones

Assays to determine DNA repair ability

El papel clave de las histonas

Alternative PCR-RFLP methods for mussel Mytilus species identification

EVALUATION OF GENOTOXICITY IN GILLS AND HEMOLYMPH OF CLAM RUDITAPES DECUSSATUS FED WITH THE TOXIC DINOFLAGELLATE PROROCENTRUM LIMA

Special Issue: Current Studies in Environmental Biomonitoring and Ecotoxicology in Spain PREFACE

Biomonitoring of a population of Portuguese workers exposed to lead

Sharp decrease of genetic variation in two Spanish localities of razor clam Ensis siliqua: natural fluctuation or Prestige oil spill effects?

Use of three bivalve species for biomonitoring a polluted estuarine environment

Synthesis, characterization, reactivity and catalytic activity of oxidovanadium(IV), oxidovanadium(V) and dioxidovanadium(V) complexes of benzimidazole modified ligands

Synthesis, crystal structure and magnetic properties of new dinuclear Mn(III) compounds with 4-ClC6H4COO and 4-BrC6H4COO bridges

Enantio- and Diastereoselective Organocatalytic ¿-Alkylation of Aldehydes with 3-Substituted 2-(Bromomethyl)acrylates

Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1 alpha,25-Dihydroxyvitamin D-3 with Substituents at C18

Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and gamma H2AX analysis

Monitoring follow up of two areas affected by the Prestige oil four years after the spillage

Induction of oxidative DNA damage by the marine toxin okadaic acid depends on human cell type

Synthesis and characterization of metallodendritic palladium-biscarbene complexes derived from 1,1 ¿-methylenebis(1,2,4-triazole)

Comparison Between Two Bivalve Species as Tools for the Assessment of Pollution Levels in an Estuarian Environment

Synthesis, characterization and catalytic activities of vanadium complexes containing ONN donor ligand derived from 2-aminoethylpyridine

Okadaic acid induces morphological changes, apoptosis and cell cycle alterations in different human cell types

Strong genetic differentiation among east Atlantic populations of the sword razor shell (Ensis siliqua) assessed with mtDNA and RAPD markers

Vanadium(IV) and -(V) Complexes of Reduced Schiff Bases Derived from Aromatic o-Hydroxyaldehydes and Tyrosine Derivatives

Copper(II) complex of monobasic tridentate ONN donor ligand: synthesis, encapsulation in zeolite-Y, characterization, and catalytic activity

Synthesis, characterisation and catalytic activities of vanadium complexes containing ONN donor ligand (E)-4-[(2-(dimethylamino)ethylimino] methyl-5-(hydroxymethyl)-2-methylpyridin-3-ol

Birth-and-Death Long-Term Evolution Promotes Histone H2B Variant Diversification in the Male Germinal Cell Line

Isolation and characterization of microsatellite markers in the queen scallop Aequipecten opercularis and their application to a population genetic study.

The Organic Selenium Compound Selenomethionine Modulates Bleomycin-Induced DNA Damage and Repair in Human Leukocytes

Isolation of twelve microsatellite markers in the pullet carpet shell Venerupis pullastra (Bivalvia: Veneridae)

In vitro evaluation of selenium genotoxic, cytotoxic, and protective effects: a review

X-ray Diffraction, Solution Structure, and Computational Studies on Derivatives of (3-sec-Butyl-2,3-dihydro-1H-isoquinolin-4-ylidene)acetic Acid: Compounds with Activity as Calpain Inhibitors

The importance of the in vitro genotoxicity evaluation of food components: the selenium

Polymer-Bound Oxidovanadium(IV) and Dioxidovanadium(V) Complexes as Catalysts for the Oxidative Desulfurization of Model Fuel Diesel

Assessment of okadaic acid effects on cytotoxicity, DNA damage and DNA repair in human cells

Review on the effects of exposure to spilled oils on human health

Titanium(IV)-Salan Catalysts for Asymmetric Sulfoxidation with Hydrogen Peroxide

A short practical approach to 24R,25-dihydroxyvitamin D3

Genotoxicity evaluation of exposure to lead

A 4-Hydroxypyrrolidine-Catalyzed Mannich Reaction of Aldehydes: Control of anti-Selectivity by Hydrogen Bonding Assisted by Bronsted Acids

Genotoxic effects of lead: An updated review

Evolutionary Dynamics of the 5S rDNA Gene Family in the Mussel Mytilus: Mixed Effects of Birth-and-Death and Concerted Evolution.

Vanadium complexes having [VIVO]2+ and [VVO2]+ cores with binucleating dibasic tetradentate ligands: Synthesis, characterization, catalytic and antiamoebic activities

Better Performance of Monodentate P-Stereogenic Phosphanes Compared to Bidentate Analogues in Pd-Catalyzed Asymmetric Allylic Alkylations

Polymer-bound oxidovanadium(IV) and dioxidovanadium(V) complexes: synthesis, characterization and catalytic application for the hydroamination of styrene and vinyl pyridine

Vanadium-salen and -salan complexes: characterization and application in oxygen transfer reactions

Histone genes of the razor clam solen marginatus unveil new aspects of linker histone evolution in protostomes

Highly Enantioselective Conjugate Additions of Aldehydes to Vinyl Sulfones

Synthesis and characterization of Ru(arene) complexes of bispyrazolylazines: Catalytic hydrogen transfer of ketones

Vanadium compounds as therapeutic agents: Some chemical and biochemical studies

Isolation of twelve microsatellite markers in the pullet carpet shell venerupis pullastra (bivalvia:veneridae)

Intron characterization and their potential as molecular markers for population studies in the scallops Aequipecten opercularis and Mimachlamys varia

Conjugate Addition of Nitroalkanes to an Acrylate Equivalent. Activation Stereocontrol at C-a of the Nitro Group through Double Catalytic Nuclease Activity

Single nucleotide polymorphism for population studies in the scallops aequipecten opercularis and mimachlamys varia

Two different size classes of 5S rDNA units coexisting in the same tandem array in the razor clam ensis macha: is this region suitable for phylogeographic studies?

Influence of polydentate ligands in the structure of dinuclear vanadium compound

(1,3,4-Oxadiazole)copper(II) Compounds: Dimensionality, Magnetism and Nuclease Activity

DNA damage related to exposure to oil spills: the Prestige experience

Electronic Properties of a Cytosine Decavanadate: Toward a Better Understanding of Chemical and Biological Properties of Decavanadates

Synthesis, characterization and application of vanadium-salan complexes in oxygen transfer reactions

Biomonitoring of Human Exposure to Prestige Oil: Effects on DNA and Endocrine Parameters

Efectos genotóxicos e inmunotóxicos de la exposición laboral al plomo.

Efectos genotóxicos e inmunotóxicos de la exposición laboral al plomo

Structure, magnetic properties and nuclease activity of pyridine-2- carbaldehydethiosemicarbazonecopper(II) complexes

Genetic analysis of Aequipecten opercularis and Mimachlamys varia (Bivalvia: Pectinidae) in several Atlantic and Mediterranean localities, revealed by mitochondrial PCR-RFLPs: a preliminary study.

Identification of razor clams Ensis arcuatus and Ensis siliqua by PCR-RFLP analysis of ITS1 region.

Evaluación del efecto de la selenometionina sobre la reparación del daño en el ADN

Relationship between blood concentrations of heavy metals and cytogenetic and endocrine parameters among subjects involved in cleaning coastal areas affected by the "Prestige" tanker oil spill.

Single nucleotide polymorphism for population studies in the scallops Aequipecten opercularis and Mimachlamys varia.

Cytogenetic effects induced by Prestige oil on human populations: The role of polymorphisms in genes involved in metabolism and DNA repair

Genome sizes and karyotypes in the razor clams Ensis arcuatus (Jeffreys, 1865) and E. siliqua (Linnaeus, 1758).

Self-assembly of Ligands Designed for the Building of a New Type of [2 x 2] Metallic Grid. Anion Encapsulation and Diffusion NMR Spectroscopy

A simple one-step PCR method for the identification between European and American razor clams species.

Early evolution of histone genes: prevalence of an "Orphon" H1 lineage in protostomes and birth-and-death process in the H2A family.

Sequence characterizacion and phylogenetic analysis of the 5S ribosomal DNA in some scallops (Bivalvia: Pectinidae)

Quickly evolving histones, nucleosome stability and chromatin folding: All about histone H2A.Bbd.

Genetic variation of the razor clam Ensis siliqua (Jeffreys, 1875) along the European coast based on random amplified polymorphic DNA markers

PuPHOS and CamPHOS Ligands in the Intermolecular Catalytic Pauson-Khand Reaction

Synthesis of two carboxylic haptens for raising antibodies to 25-Hydroxyvitamin D3 and 1á,25-Dihydroxyvitamin D3

Synthesis and catalytic applications of C1 symmetric group 4 ansa- metallocene complexes

Synthesis and crystal structure of manganese(II) complexes with high-denticity ligands derived from azacrowns

Identification of the Razor Clam Species Ensis arcuatus, E. siliqua, E. directus, E. macha, and Solen marginatus Using PCR-RFLP Analysis of the 5S rDNA Region

Biomonitorización de la exposición ocupacional a hidrocarburos. Un TEST revelador.

Highly condensed cyclic carbohydrates derived from a common precursor

(Arene)ruthenium(II) complexes containing substituted bis(pyrazolyl)methane ligands - catalytic behaviour in transfer hydrogenation of ketones

Effect of Protonation and Interaction with Anions on a Lead(II) Complex with a Lateral Macrobicycle Containing a Phenol Schiff-Base Spacer